Volume 10, Number 6—June 2004
Dispatch
SARS and Common Viral Infections
Janice K. Louie*†1
, Jill K. Hacker*1, Jennifer Mark*, Shilpa S. Gavali*, Shigeo Yagi†, Alex Espinosa†, David P. Schnurr†, Cynthia K. Cossen†, Erin R. Isaacson†, Carol A. Glaser†, Marc Fischer‡, Arthur L. Reingold†, Duc J. Vugia*†, and for the Unexplained DeathsCritical Illnesses Working Group
, Jill K. Hacker*1, Jennifer Mark*, Shilpa S. Gavali*, Shigeo Yagi†, Alex Espinosa†, David P. Schnurr†, Cynthia K. Cossen†, Erin R. Isaacson†, Carol A. Glaser†, Marc Fischer‡, Arthur L. Reingold†, Duc J. Vugia*†, and for the Unexplained DeathsCritical Illnesses Working Group
Table 2
Detection of respiratory pathogens by polymerase chain reaction (PCR), culture, and serologic testing for cases tested at the California Department of Health Servicesa
| PCR (N = 151) |
Culture (N = 154) |
Serologic testingb (N = 78) |
|
|---|---|---|---|
| n (%) | n (%) | n (%) | |
| Influenza A | 27 (18)c | 9 (6) | 4 (5)d |
| Influenza B | 1 (1) | 1 (1) | 1 (1)d |
| Respiratory syncytial virus | 5 (3) | 1 (1) | 1 (1)d |
| Parainfluenza virus types 2–4 | 6 (5) | 5 (4) | 0 |
| Human metapneumovirus | 11 (7) | 0 | ND |
| Coronavirus OC43 | 1 (1) | 0 | ND |
| Coronavirus 229E | 0 | 0 | ND |
| Parainfluenza virus type 1 | 0 | 0 | ND |
| Adenovirus | 0 | 0 | 1 (1)d |
| Picornavirus | 12 (8) | 0 | ND |
| Mycoplasma pneumoniae | 0e | ND | 3 (4)c |
| Chlamydia spp. | 0e | ND | 1 (1) |
| SARS-CoV | 0 | 0 | 2 (3) |
| Total positive | 63 (42) | 16 (10) | 13 (17) |
aND, not done; SARS-CoV, severe acute respiratory syndrome–associated coronavirus.
bMeasured as a significant rise in immunoglobulin (Ig) G in paired serum samples for all specimens except one positive for M. pneumoniae IgM.
cSpecimens from one case-patient positive for influenza A (by PCR and culture) were also positive for M. pneumoniae IgM.
dOne specimen negative by culture.
eChlamydia pneumoniae PCRs were performed retrospectively only on specimens from patients with serologic evidence of M. pneumoniae (n = 3) and Chlamydia spp. (n = 1) infection.
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