Volume 13, Number 2—February 2007
Research
Reduced Efficacy of Insecticide-treated Nets and Indoor Residual Spraying for Malaria Control in Pyrethroid Resistance Area, Benin
Raphael N’Guessan*, Vincent Corbel†, Martin Akogbéto‡§, and Mark Rowland
Table 6
Molecular and biochemical assays* conducted on samples of Anopheles gambiae from Malanville and Ladji compared with laboratory-susceptible (Kisumu) and pyrethroid-resistant kdr (Vkper) strains†
| Populations or strains | N | Frequency of kdr (%) | Oxidase nmol P450 U/mg† | α-esterase μmol/min/mg | β-esterase μmol/min/mg |
|---|---|---|---|---|---|
| Kisumu | 40 | 0 | 0.15 (± 0.020)‡ | 0.11 (± 0.019)‡§ | 0.12 (± 0.016)‡ |
| Malanville | 45 | 6 | 0.25 (± 0.018)§ | 0.07 (± 0.017)‡ | 0.04 (± 0.015)§ |
| Ladji | 45 | 83 | 0.27 (± 0.018)§ | 0.18 (± 0.017)¶ | 0.15 (± 0.014)‡¶ |
| Vkper | 47 | 100 | 0.13 (± 0.017)‡ | 0.11 (± 0.017)§¶ | 0.14 (± 0.014)¶ |
*Mean enzymatic activity ± SE (standard error).
In each column, values not sharing the same superscript are significantly different at the 5% level.
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