Volume 11, Number 8—August 2005
Research
Coxiella burnetii Genotyping
Olga Glazunova*1, Véronique Roux*1, Olga Freylikman*†, Zuzana Sekeyova*‡, Ghislain Fournous*, Judith Tyczka§, Nikolai Tokarevich†, Elena Kovacova‡, Thomas J. Marrie¶, and Didier Raoult*
Table A1
Isolates of Coxiella burnetii studied
| Isolate | Origin | Disease, symptoms, clinical status | Geographicsource | ST (sequence type) | Plasmid sequence type |
|---|---|---|---|---|---|
| CB108 | Human blood | Acute | Marseille, France, 2001 | 1 | QpDV |
| CB1 | Human heart valve | Chronic | Istres, France, 1989 | 1 | QpDV |
| CB3 | Human heart valve | Chronic | Marseille, France | 1 | QpDV |
| CB36 | Human placenta | Abortion | Martigues, France, 1992 | 1 | QpDV |
| CB38 | Human blood | Acute | Marseille, France, 1992 | 1 | QpDV |
| CB41 | Human heart valve | Chronic | Marseille, France, 1993 | 1 | QpDV |
| CB60 | Human blood | Acute | Marseille, France, 1996 | 1 | QpDV |
| CB63 | Human heart valve | Chronic | Marseille, France, 1994 | 1 | QpDV |
| CB75 | Human blood | Chronic | Marseille, France, 1998 | 1 | QpDV |
| CB82 | Human blood | Acute | Marseille, France, 1999 | 1 | QpDV |
| CB86 | Human blood | Chronic | Marseille, France, 1999 | 1 | QpDV |
| CB87 | Human placenta | Abortion | Martigues, France, 1999 | 1 | QpDV |
| CB89 | Human placenta | Abortion | Martigues, France, 2000 | 1 | QpDV |
| CB94 | Human blood | Acute | Aix en Provence, France, 2000 | 1 | QpDV |
| CB97 | Human blood | Acute | Marseille, France, 2000 | 1 | QpDV |
| CB110 | Human blood | Chronic | Marseille, France, 2002 | 1 | QpDV |
| CB28 | Human blood | Acute | Salon de Provence, France, 1992 | 1 | QpDV |
| CB26 | Human blood | Acute | Marseille, France, 1992 | 1 | QpDV |
| CB64 | Human blood | Acute | Martigues, France, 1996 | 1 | QpDV |
| CB39 | Human blood | Acute | Marseille, France, 1992 | 2 | QpDV |
| RT-1140 | Human blood | Pneumonia | Krimea, Ukrain 1954 | 2 | QpDV |
| RT-Schperling | Human blood | Fever | Kyrgyzstan, 1955 | 2 | QpDV |
| CB118 | Human heart valve | Chronic | Marseille, France, 2004 | 3 | QpDV |
| CB62 | Human blood | Acute | Martigues, France, 1996 | 4 | QpDV |
| CB20 | Human blood | Acute | Salon de Provence, France, 1991 | 4 | QpRS |
| CB51 | Human placenta | Abortion | Madrid, Spain, 1996 | 4 | QpDV |
| CB12 | Human blood | Acute | Aix en Provence, France | 4 | QpDV |
| CB57 | Human blood | Acute | Martigues, France, 1996 | 4 | QpDV |
| CB54 | Human blood | Acute | Aix en Provence, France, 1996 | 4 | QpDV |
| CB111 | Human heart valve | Chronic | Marseille, France, 2003 | 5 | QpRS |
| CB35 | Human heart valve | Chronic | Paris, France, 1992 | 5 | QpRS |
| CB45 | Human heart valve | Chronic | Paris, France, 1993 | 6 | QpRS |
| CB43 | Human heart valve | Chronic | Paris, France, 1993 | 7 | QpRS |
| Leningrad-2 | Human blood | - | Leningrad, Russia, 1955 | 7 | QpRS |
| Leningrad-4 | Human blood | - | Leningrad, Russia, 1957 | 7 | QpRS |
| CB10 | Human heart valve | Chronic aneurysm | Grenoble, France | 8 | QpRS |
| CB9 | Human blood | Chronic | Lyon, France | 8 | QpRS |
| CB31 | Human heart valve | Chronic | Marseille, France, 1992 | 8 | QpRS |
| CB34 | Human blood | Chronic | Marseille, France, 1992 | 8 | QpRS |
| CB44 | Human heart valve | Chronic | Créteil, France, 1993 | 8 | QpRS |
| CB53 | Aneurysm | Chronic | Marseille, France, 1995 | 8 | QpRS |
| CB61 | Valvular prosthesis | Chronic | Marseille, France, 1996 | 8 | QpRS |
| CB70 | Human heart valve | Chronic | Grenoble, France, 1997 | 8 | QpRS |
| CB71 | Valvular prosthesis | Chronic | Saint-Laurent du Var, France, 1997 | 8 | QpRS |
| CB73 | Valvular prosthesis | Chronic | Marseille, France, 1998 | 8 | QpRS |
| CB81 | Human heart valve | Chronic | Madrid, Spain, 1999 | 8 | QpRS |
| CB91 | Valvular prosthesis | Chronic | Marseille, France, 2000 | 8 | QpRS |
| CB93 | Human placenta | Abortion | Dreux, France, 2000 | 8 | QpRS |
| CB95 | Human blood | Chronic | Marseille, France, 2000 | 8 | QpRS |
| CB116 | Aneurysm | Chronic | Marseille, France, 2003 | 8 | QpRS |
| CB107 | Human heart valve | Chronic | Tours, France, 2001 | 8 | QpRS |
| CB96 | Human heart valve | Chronic | Marseille, France, 2000 | 8 | QpRS |
| CB114 | Human heart valve | Chronic | Marseille, France, 2003 | 8 | QpRS |
| CB15 | Human heart valve | Chronic | Lyon, France, 1991 | 8 | QpRS |
| CB47 | Human heart valve | Chronic | Barcelone, Spain, 1994 | 8 | QpRS |
| CB99 | Human heart valve | Chronic | Marseille, France, 2000 | 8 | QpRS |
| CB106 | Human heart valve | Chronic | Toulouse, France, 2001 | 8 | QpRS |
| CB79 | Human heart valve | Chronic | Paris, France, 1999 | 8 | QpRS |
| CB98 | Human heart valve | Chronic | Marseille, France, 2000 | 8 | QpRS |
| CB83 | Goat placenta | Abortion | Newfoundland, USA, 1999 | 8 | QpRS |
| CB8 | Human heart valve | Chronic | Marseille, France, 1990 | 8 | QpRS |
| Priscilla | Aborted goat | Abortion | Montana, USA, 1980 | 8 | QpRS |
| CB117 | Human heart valve | Chronic | Marseille, France, 2004 | 8 | QpRS |
| CB32 | Human heart valve | Chronic | Lyon, France, 1992 | 9 | QpRS |
| CB92 | Human heart valve | Chronic | Marseille, France, 2000 | 9 | QpRS |
| CB68 | Pigeon excrement | – | Marseille, France, 1996 | 9 | QpRS |
| CB49 | Human heart valve | Chronic | Marseille, France, 1994 | 9 | QpRS |
| CB65 | Human heart valve | Chronic | Marseille, France, 1996 | 10 | QpRS |
| CB103 | Ewe placenta | Abortion | Marseille, France, 2001 | 10 | QpRS |
| CB13 | Human blood | Chronic | Paris, France | 11 | QpH1/QpDV |
| CB40 | Human heart valve | Chronic | Paris, France, 1993 | 11 | QpH1 |
| CB46 | Valvular prosthesis | Chronic | Paris, France, 1993 | 11 | QpH1 |
| CB5 | Human blood | Chronic | Paris, France, 1990 | 12 | QpH1 |
| CB6 | Human blood | Chronic | Paris, France | 12 | QpH1 |
| CB42 | Valvular prosthesis | Chronic | Toulouse, France, 1993 | 12 | QpH1 |
| CB52 | Valvular prosthesis | Chronic | Paris, France, 1995 | 12 | QpH1 |
| CB56 | Human heart valve | Chronic | Paris, France, 1996 | 12 | QpH1 |
| CB58 | Spleen abscess | – | Lyon, France, 1996 | 12 | QpH1 |
| CB76 | Human heart valve | Chronic | Paris, France, 1998 | 12 | QpH1 |
| CB105 | Human heart valve | Chronic | Montpellier, France, 2001 | 12 | QpH1 |
| CB112 | Human heart valve | Chronic | Zurich, Switzerland, 2003 | 12 | QpH1 |
| CB109 | Human heart valve | Chronic | Berlin, Germany, 2002 | 12 | QpH1 |
| CB113 | Goat placenta | Abortion | Albi, France, 2003 | 12 | QpH1 |
| CB33 | Human heart valve | Chronic | Clermont-Ferrand, France, 1992 | 12 | QpH1 |
| CB55 | Vegetation | Chronic | Paris, France, 1996 | 12 | QpH1 |
| CB2 | Human blood | Immunodepression | Toulouse, France, | 13 | QpH1 |
| CB69 | Vegetation | Chronic | Toulouse, France, 1996 | 13 | QpH1 |
| CB85 | Human blood | Chronic | Tours, France, 1999 | 14 | QpH1 |
| CB74 | Valvular prosthesis | Chronic | Toulouse, France, 1998 | 14 | QpH1 |
| CB59 | Aneurysm | Chronic aneurysm | Saint-Etienne, France, 1996 | 14 | QpH1 |
| CB80 | Node | Chronic | Niort, France, 1999 | 14 | QpH1 |
| Z3055 | Ewe placenta | Abortion | Germany | 14 | QpH1 |
| CB102 | Valvular prosthesis | Chronic | Poitiers, France, 2001 | 15 | QpH1 |
| CB11 | Human blood | Acute | Marseille, France | 16 | QpH1 |
| CB23 | Human blood | Chronic | Clermont-Ferrand, France, 1988 | 16 | QpH1 |
| Brasov | Human | Acute | Romania | 16 | QpH1 |
| Bangui | Human blood | Acute | Central Africa | 16 | QpH1 |
| California | Cow milk | Persistent | California, USA, 1947 | 16 | QpH1 |
| CB25 | Human blood | Acute | Paris, France, 1991 | 16 | QpH1 |
| Dyer | Human blood | Acute | USA, 1938 | 16 | QpH1 |
| Ohio | Cow milk | Persistent | Ohio, USA, 1956 | 16 | QpH1 |
| Nine Mile | Tick | – | Montana, USA, 1935 | 16 | QpH1 |
| CS-KL 9 | Ixodes ricinus | – | Slovakia, 1989 | 16 | QpH1 |
| Z-2775/90 | Cow placenta | Abortion | Germany, 1990 | 16 | QpH1 |
| J-1 | Cow milk | – | Japan | 16 | QpH1 |
| J-3 | Cow milk | – | Japan | 16 | QpH1 |
| J-27 | Cow milk | – | Japan | 16 | QpH1 |
| J-60 | Cow milk | – | Japan | 16 | QpH1 |
| J-82 | Cow milk | – | Japan | 16 | QpH1 |
| Hardthof | Cow milk | – | Germany, 1990 | 16 | QpH1 |
| CB77 | Human heart valve | Chronic | Paris, France, 1998 | 17 | QpH1 |
| CB100 | Human blood | Chronic | Strasbourg, France | 18 | QpH1 |
| Henzerling | Human blood | Acute | Italy/Slovakia, 1945 | 18 | QpH1 |
| Balaceanu | Human | Acute | Romania | 18 | QpH1 |
| Geier | Human | Acute | Romania | 18 | QpH1 |
| Heizberg | Human | Acute | Greece | 18 | QpH1 |
| Cs-Florian | Human blood | – | Slovakia, 1956 | 18 | QpH1 |
| Z-3464/92 | Goat placenta | Abortion | Germany, 1992 | 18 | QpH1 |
| Z-4488/93 | Ewe placenta | Abortion | Germany, 1993 | 18 | QpH1 |
| Z-349-36/94 | Ewe placenta | – | Germany, 1994 | 18 | QpH1 |
| München | Sheep | – | München, Germany, 1969 | 18 | QpH1 |
| CB119 | Human heart valve | Chronic | Senegal, 2004 | 19 | QpH1 |
| CB48 | Human placenta | Abortion | Grenoble, France, 1994 | 20 | QpH1 |
| CB50 | Valvular prosthesis | Chronic | Paris, France, 1994 | 20 | QpH1 |
| CB66 | Aneurysm | Chronic aneurysm | Marseille, France, 1996 | 20 | QpH1 |
| CB72 | Valvular prosthesis | Chronic | Paris, France, 1996 | 20 | QpH1 |
| CB78 | Valvular prosthesis | Chronic | Marseille, France, 1998 | 20 | QpH1 |
| CB88 | Human heart valve | Chronic | Lyon, France, 1999 | 20 | QpH1 |
| CB90 | Human heart valve | Chronic | Lyon, France,2000 | 20 | QpH1 |
| Z-3567/92 | Cow placenta | Abortion | Germany, 1992 | 20 | QpH1 |
| Dugway 5J108-111 | Rodent | – | Utah, USA, 1958 | 20 | QpH1 |
| CB4 | Human blood | Chronic | Montpellier, France,1988 | 21 | QpH1 |
| CB7 | Human heart valve | Chronic Aneurysm | Marseille, France | 21 | QpH1 |
| Q229 | Human heart valve | Chronic | Nova Scotia, Canada, 1982 | 21 | QpH1 |
| Dog CB | Dog uterus | – | Nova Scotia, Canada, 1995 | 21 | |
| Poker Cat | Cat | – | Nova Scotia, Canada, 1986 | 21 | |
| CBNSC1 | Cat | – | Nova Scotia, Canada, 1986 | 21 | QpH1 |
| Dog ut Ad | Dog uterus | – | Nova Scotia, Canada, 1989 | 21 | |
| CB115 | Human heart valve | Chronic | Nova Scotia, Canada, 2003 | 21 | |
| Q212 | Human heart valve | Chronic | Nova Scotia, Canada, 1981 | 21 | |
| Scurry Q217 | Human liver biopsy | Hepatitis | Rocky Mountain, USA | 21 | |
| 48 | Haemaphysalis punctata | – | Slovakia, 1970 | 22 | QpH1 |
| Irkutsk | Tick | – | Irkutsk, Russia1969 | 23 | QpH1 |
| Uzbekistan | Cow placenta | – | Uzbekistan, 1971 | 23 | QpH1 |
| 1894 | Liver and spleen of wild bird | – | Czechoslovakia, 1954 | 23 | QpH1 |
| Kazakhstan-6 | Dermacentor marginatus | – | Kazakhstan, 1969 | 23 | QpH1 |
| K-261-Louga | Cow milk | – | Leningrad, Russia, 1959 | 23 | QpH1 |
| Kazakhstan -5 | Dermacentor hirundinis | – | Kazakhstan, 1969 | 23 | QpH1 |
| Russet mouse | Russet mouse viscera | – | Pskov, Russia | 23 | QpH1 |
| II/IA | Dermacentor marginatus | – | Slovakia, 1972 | 23 | QpH1 |
| IXO | Ixodes ricinus | – | Czech Republic, 1957 | 23 | QpH1 |
| Mongolia-2 | Dermacentor nuttalli | – | Mongolia, 1985 | 23 | QpH1 |
| CS-27 | Dermacentor marginatus | – | Slovakia, 1972 | 23 | QpH1 |
| Oufa-1 | Human blood | – | Oufa, Russia | 23 | QpH1 |
| Oufa-2 | Ewe placenta | Abortion | Oufa, Russia | 23 | QpH1 |
| Louga-3 | Ixodes ricinus | – | Leningrad, Russia, 1962 | 23 | QpH1 |
| Louga-2 | Ixodes ricinus | – | Leningrag, Russia, 1959 | 23 | QpH1 |
| Louga-1 | Cimex lecturalius | – | Leningrad, Russia, 1959 | 23 | QpH1 |
| Louga rodent | Apodemus flavicollis viscera | – | Leningrad, Russia, 1958 | 23 | QpH1 |
| Mongolia-1 | Dermacentor silvarum | – | Mongolia, 1984 | 23 | QpH1 |
| Vologda-2 | Human blood | – | Vologda, Russia, 1987 | 23 | QpH1 |
| 8931 F10 | Cow placenta | Abortion | Germany | 24 | QpH1 |
| Grita | - | – | Germany, 1940-1945 | 25 | QpH1 |
| M-44 | Vaccine | – | Russia | 25 | QpH1 |
| Kazakhstan-4 | Fly | – | Kazakhstan, 1965 | 25 | QpH1 |
| Termez | Human blood | – | Uzbekistan, 1952 | 26 | QpRS |
| Z2534 | Goat placenta | Abortion | Austria | 27 | QpH1 |
| Kazakhstan-1 | Ewe placenta | Abortion | Kazakhstan | 28 | QpRS |
| Kazakhstan-2 | Cow milk | – | Kazakhstan, 1962 | 28 | QpRS |
| Kazakhstan-3 | Hyalomma tick | – | Kazakhstan, 1962 | 28 | QpRS |
| Tcheredov | Human blood | – | Kazakhstan, 1965 | 28 | QpRS |
| Henzerling-r * | Human blood | – | Italy, 1945 / Slovakia, | 29 | QpH1 |
| Namibia | Goat | – | Namibia, 1991 | 30 | QpRS |
*Strain resistant to chlortetracycline obtained by passages in embryonated hen's eggs in presence of increasing doses of chlortetracycline.
1Dr. Glazunova and Dr. Roux contributed equally to this work.
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Page updated: April 23, 2012
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