Volume 12, Number 9—September 2006
Research
Genomic Signatures of Human versus Avian Influenza A Viruses
Table A3
Scanning for amino acid 'signatures' for influenza A virus PB2 protein |
||||||||
---|---|---|---|---|---|---|---|---|
Pos | Avian |
Human |
Comments | PR8 | ||||
Con | Ent | Residues | Con | Ent | Residues | |||
1 | M | -0.500 | M(76),-(19), | M | -0.055 | M(303),-(3), | ||
2 | E | -0.293 | E(88),K(1),-(6), | E | -0.061 | E(303),V(1),-(2), | Nearly Identical | |
3 | R | -0.175 | R(91),-(4), | R | -0.022 | R(305),T(1), | Nearly Identical | |
4 | I | -0.140 | I(92),-(3), | I | -0.022 | I(305),L(1), | Nearly Identical | |
5 | K | -0.140 | K(92),-(3), | K | -0.039 | R(2),K(304), | Nearly Identical | |
6 | E | -0.140 | E(92),-(3), | E | 0.000 | E(306), | Nearly Identical | |
7 | L | -0.160 | L(92),F(1),-(2), | L | 0.000 | L(306), | Nearly Identical | |
8 | R | -0.160 | R(92),W(1),-(2), | R | 0.000 | R(306), | Nearly Identical | |
9 | D | -0.521 | N(1),D(83),E(7),Y(2),-(2), | N | -0.619 | N(227),D(1),S(2),T(76), | ||
10 | L | -0.160 | I(1),L(92),-(2), | L | -0.022 | I(1),L(305), | Nearly Identical | |
11 | M | -0.117 | I(1),M(93),-(1), | M | 0.000 | M(306), | Nearly Identical | |
12 | S | 0.000 | S(95), | S | -0.022 | L(1),S(305), | Nearly Identical | |
13 | Q | 0.000 | Q(95), | Q | 0.000 | Q(306), | Same | |
14 | S | 0.000 | S(95), | S | -0.022 | F(1),S(305), | Nearly Identical | |
15 | R | 0.000 | R(95), | R | 0.000 | R(306), | Same | |
16 | T | -0.058 | S(1),T(94), | T | 0.000 | T(306), | Nearly Identical | |
17 | R | 0.000 | R(95), | R | 0.000 | R(306), | Same | |
18 | E | 0.000 | E(95), | E | 0.000 | E(306), | Same | |
19 | I | 0.000 | I(95), | I | 0.000 | I(306), | Same | |
20 | L | 0.000 | L(95), | L | -0.022 | L(305),V(1), | Nearly Identical | |
21 | T | 0.000 | T(95), | T | 0.000 | T(306), | Same | |
22 | K | 0.000 | K(95), | K | -0.022 | N(1),K(305), | Nearly Identical | |
23 | T | 0.000 | T(95), | T | -0.022 | P(1),T(305), | Nearly Identical | |
24 | T | 0.000 | T(95), | T | 0.000 | T(306), | Same | |
25 | V | 0.000 | V(95), | V | 0.000 | V(306), | Same |
1These authors contributed equally to this article.
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