Volume 19, Number 6—June 2013
Research
Characteristics of Group A Streptococcus Strains Circulating during Scarlet Fever Epidemic, Beijing, China, 2011
Peng Yang1, Xiaomin Peng1, Daitao Zhang, Shuangsheng Wu, Yimeng Liu, Shujuan Cui, Guilan Lu, Wei Duan, Weixian Shi, Shuang Liu, Jing Li, and Quanyi Wang
Table 2
Results of multivariate analyses for factors associated with 4 clinical signs of scarlet fever in patients with confirmed GAS infection, Beijing, China, 2011*
| Factor | Clinical sign of scarlet fever† |
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Strawberry tongue |
Red rash |
Pastia lines |
Circumoral pallor |
||||||||||||
| Yes, n = 293 | No, n = 354 | OR (95% CI), p value | Yes, n = 430 | No, n = 217 | OR (95% CI), p value | Yes, n = 79 | No, n = 568 | OR (95% CI), p value | Yes, n = 63 | No, n = 584 | OR (95% CI), p value | ||||
| emm type | |||||||||||||||
| 12 | 232 (79.2) | 262 (74.0) | Ref | 331 (77.0) | 163 (75.1) | Ref | 57 (72.2) | 437 (76.9) | Ref | 43 (68.3) | 451 (77.2) | Ref | |||
| 1 | 51 (17.4) | 60 (16.9) | 1.03 (0.68–1.58), 0.884 | 83 (19.3) | 28 (12.9) | 1.63 (1.01–2.62), 0.046 | 20 (25.3) | 91 (16.0) | 1.80 (1.02–3.16), 0.043 | 18 (28.6) | 93 (15.9) | 2.15 (1.17–3.93), 0.013 | |||
| Other‡ |
10 (3.4) |
32 (9.0) |
0.40 (0.19–0.84), 0.016 |
16 (3.7) |
26 (12.0) |
0.35 (0.18–0.68), 0.002 |
2 (2.5) |
40 (7.0) |
0.40 (0.09–1.72), 0.218 |
2 (3.2) |
40 (6.8) |
0.54 (0.12–2.31), 0.402 |
|||
| Age <5 y |
138 (47.1) |
108 (30.5) |
2.04 (1.46–2.83), <0.001 |
193 (44.9) |
53 (24.4) |
2.52 (1.74–3.65), <0.001 |
35 (44.3) |
211 (37.1) |
1.40 (0.86–2.27), 0.182 |
27 (42.9) |
219 (37.5) |
1.29 (0.75–2.22), 0.356 |
|||
| Female sex |
105 (35.8) |
140 (39.5) |
1.09 (0.78–1.51), 0.630 |
157 (36.5) |
88 (40.6) |
1.09 (0.77–1.55), 0.615 |
36 (45.6) |
209 (36.8) |
0.65 (0.40–1.05), 0.079 |
28 (44.4) |
217 (37.2) |
0.69 (0.40–1.18), 0.171 |
|||
| Interval >2 d§ | 51 (17.4) | 39 (11.0) | 1.87 (1.18–2.97), 0.008 | 61 (14.2) | 29 (13.4) | 1.19 (0.73–1.95), 0.489 | 7 (8.9) | 83 (14.6) | 0.58 (0.26–1.31), 0.190 | 3 (4.8) | 87 (14.9) | 0.29 (0.09–0.94), 0.040 | |||
*Four multivariate unconditional logistic regression analyses were separately conducted to examine factors for each clinical sign of scarlet fever. Scarlet fever and pharyngitis patients from whom GAS was isolated were identified as confirmed GAS patients. Boldface font indicates statistical significance. GAS, group A Streptococcus; OR, odds ratio; Ref, reference.
†Data are number (%) patients unless otherwise indicated.
‡Other emm types included types 4, 11, 22, 75, and 89.
§Interval between illness onset and hospital visit.
1These authors contributed equally to this article.
Page created: May 03, 2013
Page updated: May 03, 2013
Page reviewed: May 03, 2013
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.