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Volume 20, Number 4—April 2014
Dispatch

Diagnostic Methods for and Clinical Pictures of Polyomavirus Primary Infections in Children, Finland

Tingting ChenComments to Author , Laura Tanner, Ville Simell, Lea Hedman, Marjaana Mäkinen, Mohammadreza Sadeghi, Riitta Veijola, Heikki Hyöty, Jorma Ilonen, Mikael Knip, Jorma Toppari, Olli Simell, Maria Söderlund-Venermo, and Klaus Hedman
Author affiliations: University of Helsinki, Helsinki, Finland (T. Chen, L. Hedman, M. Sadeghi, M. Knip, M. Söderlund-Venermo, K. Hedman); Haartman Institute, Helsinki (T. Chen, L. Hedman, M. Sadeghi, M. Söderlund-Venermo, K. Hedman); University of Turku, Turku, Finland (L. Tanner, V. Simell, M. Mäkinen, J. Ilonen, J.Toppari, O. Simell); Hospital District of Southwest Finland, Turku (V. Simell, M. Mäkinen); Helsinki University Central Hospital, Helsinki (L. Hedman, M. Knip, K. Hedman); University of Oulu, Oulu, Finland (R. Veijola); University of Tampere, Tampere, Finland (H. Hyöty); Fimlab laboratories, Tampere (H. Hyöty); University of Eastern Finland, Kuopio, Finland (J. Ilonen); Tampere University Hospital, Tampere (M. Knip); Folkhälsan Research Center, Helsinki (M. Knip)

Main Article

Table

Infection-related signs and symptoms during MCPyV and TSPyV seroconversions compared with previous and subsequent intervals for asymptomatic polyomavirus infections in children, Finland, January 2011–July 2013*

Virus sign/symptom Interval, no. (%)
Previous interval
Subsequent interval
No. (%) p value No. (%) p value
MCPyV seroconversion, n = 45
URTI 14 (31.8) 10 (22.2) 0.4545 18 (41.9) 0.3018
LRTI 3 (6.8) 2 (4.4) 1.0000 3 (7.0) 1.0000
Fever without RTI 2 (6.8) 2 (4.4) 1.0000 3 (7.0) 0.6250
Gastroenteritis 9 (20.5) 9 (20.0) 1.0000 11 (25.6) 0.5488
Acute tonsillitis 1 (2.3) 0 ND 1 (2.3) 1.0000
Acute otitis media 10 (22.7) 11 (24.4) 1.0000 13 (30.2) 0.6291
Acute conjunctivitis 2 (4.5) 1 (2.2) 1.0000 1 (2.3) 1.0000
Exanthema 7 (15.9) 1 (2.2) 0.0703 1 (2.3) 0.0703
Acute sinusitis 2 (4.5) 0 ND 1 (2.3) 1.0000
Total 32 (72.7) 26 (57.8) 0.2632 31 (72.1) 1.0000
No data
1

0
NA

2
NA
TSPyV seroconversion, n = 39
URTI 14 (35.9) 9 (23.1) 0.3593 13 (35.1) 1.0000
LRTI 3 (7.7) 3 (7.7) 1.0000 2 (5.4) 1.0000
Fever without RTI 2 (5.1) 5 (12.8) 0.3750 4 (10.8) 0.6875
Gastroenteritis 10 (25.6) 12 (30.8) 0.7744 5 (13.5) 0.3877
Acute tonsillitis 1 (2.6) 1 (2.6) 1.0000 2 (5.4) 1.0000
Acute otitis media 8 (20.5) 12 (30.8) 0.3877 8 (21.6) 1.0000
Acute conjunctivitis 4 (10.3) 5 (12.8) 1.0000 3 (8.1) 1.0000
Exanthema 2 (5.1) 3 (7.7) 1.0000 1 (2.7) 1.0000
Acute sinusitis 3 (7.7) 2 (5.1) 1.0000 2 (5.4) ND
Total 32 (82.1) 30 (76.9) 0.7266 30 (81.1) 1.0000
No data
0

0
NA

2
NA
*Liddell exact test was used; p<0.05 was considered significant. MCPyV, Merkel cell polyomavirus; TSPyV, trichodysplasia spinulosa-associated polyomavirus; LRTI, lower respiratory tract infection; URTI, upper respiratory tract infection; ND, no data; NA, not applicable.

Main Article

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Page created: March 18, 2014
Page updated: March 18, 2014
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