Volume 20, Number 4—April 2014
Etymologia
Etymologia: Pertactin
On This Page
Downloads
Article Metrics
From per- (pertussis) + tactus (Latin, “to touch”), pertactin is a virulence factor of Bordetella pertussis that promotes adhesion to tracheal epithelial cells and resistance to neutrophil-mediated clearance and is a component of acellular pertussis vaccines. Pertactin-negative B. pertussis has been reported in several countries, and its prevalence in the United States has increased in recent years. However, evidence suggests that other components of current pertussis vaccines provide protection against pertactin-negative strains.
References
- Inatsuka CS, Xu Q, Vujkovic-Cvijin I, Wong S, Stibitz S, Miller JF, Pertactin is required for Bordetella species to resist neutrophil-mediated clearance. Infect Immun. 2010;78:2901–9 . DOIPubMedGoogle Scholar
- Leininger E, Roberts M, Kenimer JG, Charles IG, Fairweather N, Novotny P, Pertactin, an Arg-Gly-Asp–containing Bordetella pertussis surface protein that promotes adherence of mammalian cells. Proc Natl Acad Sci U S A. 1991;88:345–9. DOIPubMedGoogle Scholar
- Pawloski LC, Queenan AM, Cassiday PK. Prevalence and molecular characterization of pertactin-deficient Bordetella pertussis in the United States. Proc Natl Acad Sci USA. 1991;88:345–9. Clin Vaccine Immunol. 2014;21:119–25. DOIPubMedGoogle Scholar
Related Links
Table of Contents – Volume 20, Number 4—April 2014
| EID Search Options |
|---|
Advanced Article Search – Search articles by author and/or keyword.
|
Articles by Country Search – Search articles by the topic country.
|
Article Type Search – Search articles by article type and issue.
|
Page created: February 28, 2014
Page updated: February 28, 2014
Page reviewed: February 28, 2014
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.