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Volume 21, Number 6—June 2015
Dispatch

Lack of Protection Against Ebola Virus from Chloroquine in Mice and Hamsters

Darryl Falzarano1, David Safronetz, Joseph B. Prescott, Andrea Marzi, Friederike Feldmann, and Heinz FeldmannComments to Author 
Author affiliations: National Institute of Allergy and Infectious Diseases, Hamilton, Montana, USA

Main Article

Figure 2

Survival of MA EBOV-inoculated mice (A) and hamsters (B) treated with CQ (90 mg/kg). C) Survival of MA EBOV–infected hamsters treated with a combination of CQ (50 mg/kg), doxycycline (2.5 mg/kg), and azithromycin (50 mg/kg). Combo, combination of chloroquine, doxycycline, and azithromycin; CQ, chloroquine; EBOV, Ebola virus; MA, mouse-adapted.

Figure 2. Survival of MA EBOV-inoculated mice (A) and hamsters (B) treated with CQ (90 mg/kg). C) Survival of MA EBOV–infected hamsters treated with a combination of CQ (50 mg/kg), doxycycline (2.5 mg/kg), and azithromycin (50 mg/kg). Combo, combination of chloroquine, doxycycline, and azithromycin; CQ, chloroquine; EBOV, Ebola virus; MA, mouse-adapted.

Main Article

1Current affiliation: University of Saskatchewan, Saskatoon, Saskatchewan, Canada.

Page created: May 15, 2015
Page updated: May 15, 2015
Page reviewed: May 15, 2015
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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