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Volume 21, Number 8—August 2015
Dispatch

Infections with Candidatus Neoehrlichia mikurensis and Cytokine Responses in 2 Persons Bitten by Ticks, Sweden

Anna Grankvist1, Lisa Labbé Sandelin1, Jennie Andersson, Linda Fryland, Peter Wilhelmsson, Per-Eric Lindgren, Pia Forsberg, and Christine WenneråsComments to Author 
Author affiliations: University of Gothenburg, Göteborg, Sweden (A. Grankvist, J. Andersson, C. Wennerås); Sahlgrenska University Hospital, Göteborg (A. Grankvist, J. Andersson, C. Wennerås); Kalmar County Hospital, Kalmar, Sweden (L.L. Sandelin); Uppsala University, Uppsala, Sweden (L.L. Sandelin); Linköping University, Linköping, Sweden (L. Fryland, P. Wilhelmsson, P.-E. Lindgren, P. Forsberg); County Hospital Ryhov, Jönköping, Sweden (P.-E. Lindgren)

Main Article

Figure 1

Proinflammatory cytokines in 2 patients infected with Candidatus Neoehrlichia mikurensis, Sweden. Concentrations of cytokines A) interleukin-1β (IL-1β), B) tumor necrosis factor-α (TNF-α), C) interleukin-6 (IL-6), and D) macrophage inflammatory protein-1β (MIP-1β) were measured in serum of patient 1 on days 0, 77, and 169 and in serum of patient 2 on days 0, 65, and 98. A rash developed in patient 1 on day 77 and in patient 2 on day 65. Dashed lines indicate levels of Neoehrlichia DNA in plasma

Figure 1. Proinflammatory cytokines in 2 patients infected with Candidatus Neoehrlichia mikurensis, Sweden. Concentrations of cytokines A) interleukin-1β (IL-1β), B) tumor necrosis factor-α (TNF-α), C) interleukin-6 (IL-6), and D) macrophage inflammatory protein-1β (MIP-1β) were measured in serum of patient 1 on days 0, 77, and 169 and in serum of patient 2 on days 0, 65, and 98. A rash developed in patient 1 on day 77 and in patient 2 on day 65. Dashed lines indicate levels of Neoehrlichia DNA in plasma for both patients. Dotted lines indicate detection limit for each cytokine.

Main Article

1These authors contributed equally to this article.

Page created: July 15, 2015
Page updated: July 15, 2015
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