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Volume 23, Number 5—May 2017
Research

Invasive Nontuberculous Mycobacterial Infections among Cardiothoracic Surgical Patients Exposed to Heater–Cooler Devices1

Meghan M. LymanComments to Author , Cheri Grigg, Cara Bicking Kinsey, M. Shannon Keckler, Heather Moulton-Meissner, Emily Cooper, Minn M. Soe, Judith Noble-Wang, Allison Longenberger, Shane R. Walker, Jeffrey R. Miller, Joseph F. Perz, and Kiran M. Perkins
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (M.M. Lyman, C. Grigg, C. Bicking Kinsey, M.S. Keckler, H. Moulton-Meissner, M.M. Soe, J. Noble-Wang, J.R. Miller, J.F. Perz, K.M. Perkins); Pennsylvania Department of Health, Harrisburg, Pennsylvania, USA (C. Bicking Kinsey, A. Longenberger, J.R. Miller); WellSpan York Hospital, York, Pennsylvania, USA (E. Cooper, S.R. Walker)

Main Article

Table 2

Descriptive characteristics of case-patients with invasive extrapulmonary NTM infections and control-patients among patients who underwent cardiothoracic surgery, York, Pennsylvania, USA, 2015*

Characteristic
 Case-patients, n = 11
 Control-patients, n = 48
 p value†
Demographics
  Age, y, mean (range) 69 (47–84) 64 (20–84) 0.33
  Male sex 9 (82) 27 (56) 0.17
  White race
 11 (100)
 45 (94)
 1.00
Predisposing medical condition
  Chronic lung disease 4 (36) 8 (17) 0.21
  COPD 1 (9) 8 (17) 1.00
  Sarcoidosis 3 (27) 0 0.005
  Diabetes 1 (9) 15 (31) 0.26
  Immunocompromised 3 (27) 10 (21) 0.69
  HIV 0 0 NA
  Transplant 0 0 NA
  Chemotherapy 2 (18) 9 (19) 1.00
  Steroid treatment 0 2 (4) 1.00
  Hematologic malignancy‡ 2 (18) 1 (2) 0.09

*Values are no. (%) patients except as indicated. COPD, chronic obstructive pulmonary disease; NA, not applicable; NTM, nontuberculous mycobacteria.
†Fisher exact test for categorical variables or two 2-sample t tests with pooled variance.
‡Among cases, hematologic malignancy included chronic lymphocytic leukemia and myelodysplastic syndrome. Among controls, hematologic malignancy included Hodgkin’s lymphoma.

Main Article

1Preliminary results from this study were presented at the Epidemic Intelligence Service conference, May 2–5, 2016, Atlanta, Georgia, USA; and the American Society for Microbiology Microbe conference, June 16–20, 2016, Boston, Massachusetts, USA.

Page created: April 17, 2017
Page updated: April 17, 2017
Page reviewed: April 17, 2017
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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