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Volume 25, Number 10—October 2019
Research

Risk Factors for Carbapenem-Resistant Pseudomonas aeruginosa, Zhejiang Province, China

Yan-Yan Hu, Jun-Min Cao, Qing Yang, Shi Chen, Huo-Yang Lv, Hong-Wei Zhou, Zuowei WuComments to Author , and Rong ZhangComments to Author 
Author affiliations: Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China (Y.-Y. Hu, H.-W. Zhou, R. Zhang); First Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou (Q. Yang); Zhejiang Provincial Hospital of Traditional Chinese Medicine, Hangzhou (J.-M. Cao, H.-Y. Lv); Hangzhou Third People’s Hospital, Hangzhou (S. Chen); Iowa State University, Ames, Iowa, USA (Z. Wu)

Main Article

Table 3

Antimicrobial resistance patterns of imipenem-resistant and imipenem-susceptible Pseudomonas aeruginosa isolates, Zhejiang Province, China, 2015–2017*

Antimicrobial drugs No. isolates (susceptibility rate, %)
 p value Total susceptibility rate, % MIC50, μg/mL
 MIC90, μg/mL
IMP-S IMP-R S R S R
Piperacillin/tazobactam 41,145 (85.70) 23,721 (44.01) <0.001 70.46 8 64 64 128
Ceftazidime 30,326 (86.26) 18,348 (47.93) <0.001 71.81 4 16 32 64
Cefepime 42,492 (89.01) 24,947 (50.83) <0.001 74.89 2 8 16 64
Aztreonam 24,215 (68.07) 13,823 (30.32) <0.001 54.35 8 32 32 64
Amikacin 42,106 (97.38) 24,748 (85.69) <0.001 93.06 2 4 8 64
Gentamicin 41,207 (92.80) 24,618 (74.29) <0.001 85.88 1 2 4 16
Ciprofloxacin 42,442 (88.28) 25,063 (51.64) <0.001 74.67 0.25 1 2 4
Levofloxacin 41,982 (89.06) 24,593 (53.17) <0.001 75.80 0.5 2 4 8
Meropenem 17,166 (96.97) 9,750 (25.36) <0.001 71.03 1 8 1 16
Colistin 1,624 (99.08) 627 (99.04) NA 99.07 1 1 1 2
Polymyxin B 5,012 (98.60) 3,746 (98.37) 0.452 98.50 1 1 2 2

*MIC50 and MIC90 were generated from the minimal inhibitory concentrations of antimicrobial drugs. Bold text indicates p values <0.05. IMP-R, imipenem-resistant; IMP-S, imipenem-susceptible; NA, not applicable; R, resistant; S, susceptible.

Main Article

Page created: September 17, 2019
Page updated: September 17, 2019
Page reviewed: September 17, 2019
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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