Genetic Characterization and Zoonotic Potential of Highly Pathogenic Avian Influenza Virus A(H5N6/H5N5), Germany, 2017–2018
Anne Pohlmann
1, Donata Hoffmann
1, Christian Grund, Susanne Koethe, Daniela Hüssy, Simone M. Meier, Jacqueline King, Jan Schinköthe, Reiner Ulrich, Timm Harder, and Martin Beer
Author affiliations: Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany (A. Pohlmann, D. Hoffmann, C. Grund, S. Koethe, J. King, J. Schinköthe, R. Ulrich, T. Harder, M. Beer); Institute of Virology and Immunology, Mittelhäusern, Switzerland (D. Hüssy); Vetsuisse Faculty Zurich, Zurich, Switzerland (S.M. Meier)
Main Article
Figure
Figure. Phylogenetic clustering and geographic distribution of highly pathogenic avian influenza A(H5N6) viruses, Europe, 2017–2018. A) Supernetwork generated by using maximum-likelihood trees of influenza virus full genomes with RAxML (https://cme.h-its.org/exelixis/web/software/raxml/index.html) and 1,000 bootstrap iterations followed by network analysis with SplitsTree4 (http://ab.inf.uni-tuebingen.de/software/splitstree4). Reassortant viruses are grouped according to their phylogenetic results. Scale bar indicates nucleotide substitutions per site. The mosaic genome structure of reassortant groups I and II is also provided. Gene segment descriptions are given in Appendix
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