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Volume 25, Number 8—August 2019
Research

Cross-Protection of Dengue Virus Infection against Congenital Zika Syndrome, Northeastern Brazil

Celia Pedroso1, Carlo Fischer1, Marie Feldmann1, Manoel Sarno, Estela Luz, Andrés Moreira-Soto, Renata Cabral, Eduardo Martins Netto, Carlos Brites, Beate M. Kümmerer, and Jan Felix DrexlerComments to Author 
Author affiliations: Universidade Federal da Bahia, Salvador, Brazil (C. Pedroso, M. Sarno, E. Luz, R. Cabral, E. Martins Netto, C. Brites); Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin Humbolt-Universität zu Berlin and Berlin Institute of Health, Institute of Virology, Berlin, Germany (C. Fischer, A. Moreira-Soto, J.F. Drexler); University of Bonn Medical Centre, Bonn, Germany (M. Feldmann, B.M. Kümmerer); German Centre for Infection Research (B.M. Kümmerer, J.F. Drexler); Martsinovsky Institute of Medical Parasitology, Tropical and Vector-Borne Diseases, Sechenov University, Moscow, Russia (J.F. Drexler)

Main Article

Figure 3

Serologic test results from participants in case–control study of cross-protection of dengue virus infection against congenital Zika syndrome, northeastern Brazil. A) Serotype-specific PRNT90 titers for cases and controls. Statistical significance (p<0.05) was calculated by the Mann–Whitney U test; no significance was found. B) Zika virus neutralizing antibody titers as a function of the number of neutralized DENV serotypes. C) Correlation of DENV and Zika virus titers. Statistical significan

Figure 3. Serologic test results from participants in case–control study of cross-protection of dengue virus infection against congenital Zika syndrome, northeastern Brazil. A) Serotype-specific PRNT90 titers for cases and controls. Statistical significance (p<0.05) was calculated by the Mann–Whitney U test; no significance was found. B) Zika virus neutralizing antibody titers as a function of the number of neutralized DENV serotypes. C) Correlation of DENV and Zika virus titers. Statistical significance (p<0.05) was calculated by Pearson correlation; no significance was found. DENV, dengue virus; NS, not significant; PRNT90, 90% plaque reduction neutralization test.

Main Article

1These authors contributed equally to this article.

Page created: July 16, 2019
Page updated: July 16, 2019
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