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Volume 27, Number 2—February 2021
Research

Plasmodium falciparum Histidine-Rich Protein 2 and 3 Gene Deletions in Strains from Nigeria, Sudan, and South Sudan

Christiane ProsserComments to Author , Karryn Gresty, John Ellis, Wieland Meyer, Karen Anderson, Rogan Lee, and Qin Cheng
Author affiliations: Australian Defence Force Malaria and Infectious Disease Institute, Brisbane, Queensland, Australia (C. Prosser, K. Gresty, K. Anderson, Q. Cheng); Westmead Institute for Medical Research, Westmead, New South Wales, Australia (C. Prosser, W. Meyer); University of Sydney, Sydney, New South Wales, Australia (C. Prosser, W. Meyer, R. Lee); QIMR–Berghofer Medical Research Institute, Brisbane (K. Gresty, K. Anderson, Q. Cheng); University of Technology Sydney, Sydney (J. Ellis); Westmead Hospital, Westmead (W. Meyer); Marie Bashir Institute for Infectious Diseases and Biosecurity, University of Sydney, Sydney (W. Meyer); Centre for Infectious Diseases and Microbiology Laboratory Services, ICPMR, Westmead Hospital, Westmead (R. Lee)

Main Article

Figure 2

Minimum spanning tree of microsatellite allelic data showing genetic relatedness of Plasmodium falciparum populations from Sudan, South Sudan, Nigeria, and Eritrea (A), and pfhrp2 and pfhrp3 deletion status of haplotypes (B) (positive: gene present; negative: gene absent). Numbered circles represent specific haplotypes. Plots were generated using PHYLOViZ software (25) with a cutoff value of 2 (minimum differences for 2 microsatellite loci) depicted as lines connecting haplotypes and a cutoff value of 3 depicted as haplotype circle arrangements/proximities.

Figure 2. Minimum spanning tree of microsatellite allelic data showing genetic relatedness of Plasmodium falciparum populations from Sudan, South Sudan, Nigeria, and Eritrea (A), and pfhrp2 and pfhrp3 deletion status of haplotypes (B) (positive: gene present; negative: gene absent). Numbered circles represent specific haplotypes. Plots were generated using PHYLOViZ software (25) with a cutoff value of 2 (minimum differences for 2 microsatellite loci) depicted as lines connecting haplotypes and a cutoff value of 3 depicted as haplotype circle arrangements/proximities.

Main Article

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Page updated: January 23, 2021
Page reviewed: January 23, 2021
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