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Volume 27, Number 4—April 2021
Research

Histopathological Characterization of Cases of Spontaneous Fatal Feline Severe Fever with Thrombocytopenia Syndrome, Japan

Yusuke SakaiComments to Author , Yuko Kuwabara, Keita Ishijima1, Saya Kagimoto, Serina Mura, Kango Tatemoto1, Ryusei Kuwata2, Kenzo Yonemitsu1, Shohei Minami, Yudai Kuroda1, Kenji Baba, Masaru Okuda, Hiroshi Shimoda, Masashi Sakurai, Masahiro Morimoto, and Ken Maeda1
Author affiliation: Yamaguchi University, Yamaguchi, Japan

Main Article

Figure 4

Necrotic foci in the liver and lung from fatal cases of severe fever with thrombocytopenia syndrome (SFTS) in cats, Japan. A, B) Hematoxylin & eosin (HE)–stained (A) and immunohistochemistry-stained (B) liver sections demonstrating SFTS virus–positive blastic lymphocytes in the necrotic foci. Scale bars indicate 100 μm. C, D) HE-stained (C) and immunohistochemistry-stained (D) lung sections demonstrating lymphocytes in the necrotic foci from the lungs. Scale bars indicates 200 μm. E, F) Ki67 (E) and Ig lambda chain (F) immunohistochemistry positively staining blastic lymphocytes. Scale bars indicates 10 μm.

Figure 4. Necrotic foci in the liver and lung from fatal cases of severe fever with thrombocytopenia syndrome (SFTS) in cats, Japan. A, B) Hematoxylin & eosin (HE)–stained (A) and immunohistochemistry-stained (B) liver sections demonstrating SFTS virus–positive blastic lymphocytes in the necrotic foci. Scale bars indicate 100 μm. C, D) HE-stained (C) and immunohistochemistry-stained (D) lung sections demonstrating lymphocytes in the necrotic foci from the lungs. Scale bars indicates 200 μm. E, F) Ki67 (E) and Ig lambda chain (F) immunohistochemistry positively staining blastic lymphocytes. Scale bars indicates 10 μm.

Main Article

1Current affiliation: National Institute of Infectious Diseases, Tokyo, Japan.

2Current affiliation: Okayama University of Science, Ehime, Japan.

Page created: February 17, 2021
Page updated: March 18, 2021
Page reviewed: March 18, 2021
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