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Volume 28, Number 12—December 2022
Synopsis

Systematic Review and Meta-analysis of Lyme Disease Data and Seropositivity for Borrelia burgdorferi, China, 2005‒2020

James H. StarkComments to Author , Xiuyan Li, Ji Chun Zhang, Leah Burn, Srinivas R. Valluri, Jiaxin Liang, Kaijie Pan, Mark A. Fletcher, Raphael Simon, Luis Jodar, and Bradford D. Gessner
Author affiliations: Pfizer Inc., Collegeville, Pennsylvania, USA (J.H. Stark, K. Pan, L. Jodar, B.D. Gessner); Yale School of Public Health, New Haven, Connecticut, USA (X. Li); Pfizer China, Beijing, China (J.C. Zhang, J. Liang); P95 Pharmacovigilance & Epidemiology, Princeton, New Jersey, USA (L. Burn); Pfizer Inc., New York, New York, USA (S.R. Valluri); Pfizer Emerging Markets, Paris, France (M.A. Fletcher); Pfizer Vaccine Research & Development, Pearl River, New York, USA (R. Simon)

Main Article

Figure 1

Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) (10) flow diagram of the 2 literature searches performed in review of seropositivity for Borrelia burgdorferi in China, 2005–2020. DALY, daily adjusted life years; LB, Lyme borreliosis; LD, Lyme disease.

Figure 1. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) (10) flow diagram of the 2 literature searches performed in review of seropositivity for Borrelia burgdorferi in China, 2005–2020. DALY, daily adjusted life years; LB, Lyme borreliosis; LD, Lyme disease.

Main Article

References
  1. Steere  AC, Strle  F, Wormser  GP, Hu  LT, Branda  JA, Hovius  JW, et al. Lyme borreliosis. Nat Rev Dis Primers. 2016;2:16090. DOIPubMedGoogle Scholar
  2. Ai  CX, Wen  YX, Zhang  YG, Wang  SS, Qiu  QC, Shi  ZX, et al. Clinical manifestations and epidemiological characteristics of Lyme disease in Hailin county, Heilongjiang Province, China. Ann N Y Acad Sci. 1988;539(1 Lyme Disease):302–13. DOIPubMedGoogle Scholar
  3. Fang  LQ, Liu  K, Li  XL, Liang  S, Yang  Y, Yao  HW, et al. Emerging tick-borne infections in mainland China: an increasing public health threat. Lancet Infect Dis. 2015;15:1467–79. DOIPubMedGoogle Scholar
  4. Wang  Y, Li  S, Wang  Z, Zhang  L, Cai  Y, Liu  Q. Prevalence and identification of Borrelia burgdorferi sensu lato genospecies in ticks from Northeastern China. Vector Borne Zoonotic Dis. 2019;19:309–15. DOIPubMedGoogle Scholar
  5. Wu  XB, Na  RH, Wei  SS, Zhu  JS, Peng  HJ. Distribution of tick-borne diseases in China. Parasit Vectors. 2013;6:119. DOIPubMedGoogle Scholar
  6. Zhang  G, Zheng  D, Tian  Y, Li  S. A dataset of distribution and diversity of ticks in China. Sci Data. 2019;6:105. DOIPubMedGoogle Scholar
  7. Eisen  L. Vector competence studies with hard ticks and Borrelia burgdorferi sensu lato spirochetes: A review. Ticks Tick Borne Dis. 2020;11:101359. DOIPubMedGoogle Scholar
  8. Zhang  ZF, Wan  KL, Zhang  JS. [Studies on epidemiology and etiology of Lyme disease in China] [in Chinese]. Zhonghua Liu Xing Bing Xue Za Zhi. 1997;18:8–11.PubMedGoogle Scholar
  9. Hao  Q, Geng  Z, Hou  XX, Tian  Z, Yang  XJ, Jiang  WJ, et al. Seroepidemiological investigation of lyme disease and human granulocytic anaplasmosis among people living in forest areas of eight provinces in China. Biomed Environ Sci. 2013;26:185–9.DOIPubMedGoogle Scholar
  10. Moher  D, Liberati  A, Tetzlaff  J, Altman  DG; PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ. 2009;339(jul21 1):b2535. DOIPubMedGoogle Scholar
  11. National Health Commission of the People’s Republic of China. GBZ 324-2019 Diagnosis of occupational Lyme disease [cited 2022 Oct 31]. http://www.nhc.gov.cn/wjw/pyl/201902/7bebbb45926347df843fab12490dc607/files/3a92b8f14083499d8347c328c28db944.pdf
  12. Branda  JA, Steere  AC. Laboratory diagnosis of Lyme borreliosis. Clin Microbiol Rev. 2021;34:e00018–9. DOIPubMedGoogle Scholar
  13. Jiang  Y, Hou  XX, Geng  Z, Hao  Q, Wan  KL. Interpretation criteria for standardized Western blot for the predominant species of Borrelia burgdorferi sensu lato in China. Biomed Environ Sci. 2010;23:341–9. DOIPubMedGoogle Scholar
  14. Dehnert  M, Fingerle  V, Klier  C, Talaska  T, Schlaud  M, Krause  G, et al. Seropositivity of Lyme borreliosis and associated risk factors: a population-based study in Children and Adolescents in Germany (KiGGS). PLoS One. 2012;7:e41321. DOIPubMedGoogle Scholar
  15. Wilking  H, Fingerle  V, Klier  C, Thamm  M, Stark  K. Antibodies against Borrelia burgdorferi sensu lato among Adults, Germany, 2008-2011. Emerg Infect Dis. 2015;21:107–10. DOIPubMedGoogle Scholar
  16. van Beek  J, Sajanti  E, Helve  O, Ollgren  J, Virtanen  MJ, Rissanen  H, et al. Population-based Borrelia burgdorferi sensu lato seroprevalence and associated risk factors in Finland. Ticks Tick Borne Dis. 2018;9:275–80. DOIPubMedGoogle Scholar
  17. Sonnleitner  ST, Margos  G, Wex  F, Simeoni  J, Zelger  R, Schmutzhard  E, et al. Human seroprevalence against Borrelia burgdorferi sensu lato in two comparable regions of the eastern Alps is not correlated to vector infection rates. Ticks Tick Borne Dis. 2015;6:221–7. DOIPubMedGoogle Scholar
  18. Cikman  A, Aydin  M, Gulhan  B, Karakecili  F, Demirtas  L, Kesik  OA. Geographical features and seroprevalence of Borrelia burgdorferi in Erzincan, Turkey. J Arthropod Borne Dis. 2018;12:378–86.PubMedGoogle Scholar
  19. Kalish  RA, McHugh  G, Granquist  J, Shea  B, Ruthazer  R, Steere  AC. Persistence of immunoglobulin M or immunoglobulin G antibody responses to Borrelia burgdorferi 10-20 years after active Lyme disease. Clin Infect Dis. 2001;33:780–5. DOIPubMedGoogle Scholar
  20. Auwaerter  PG. Diagnostic testing for Lyme disease. In: Halperin JJ, editor. Lyme Disease: an Evidence-based Approach. 2nd ed. Wallingford (UK): CABI; 2018. p. 58–75.
  21. De Keukeleire  M, Robert  A, Kabamba  B, Dion  E, Luyasu  V, Vanwambeke  SO. Individual and environmental factors associated with the seroprevalence of Borrelia burgdorferi in Belgian farmers and veterinarians. Infect Ecol Epidemiol. 2016;6:32793. DOIPubMedGoogle Scholar
  22. Tokarska-Rodak  M, Plewik  D, Kozioł-Montewka  M, Szepeluk  A, Paszkiewicz  J. [Risk of occupational infections caused by Borrelia burgdorferi among forestry workers and farmers] [in Polish]. Med Pr. 2014;65:109–17.DOIPubMedGoogle Scholar
  23. Zając  V, Pinkas  J, Wójcik-Fatla  A, Dutkiewicz  J, Owoc  A, Bojar  I. Prevalence of serological response to Borrelia burgdorferi in farmers from eastern and central Poland. Eur J Clin Microbiol Infect Dis. 2017;36:437–46. DOIPubMedGoogle Scholar
  24. Motiejunas  L, Bunikis  J, Barbour  AG, Sadziene  A. Lyme borreliosis in Lithuania. Scand J Infect Dis. 1994;26:149–55. DOIPubMedGoogle Scholar
  25. Lakos  A, Igari  Z, Solymosi  N. Recent lesson from a clinical and seroepidemiological survey: low positive predictive value of Borrelia burgdorferi antibody testing in a high risk population. Adv Med Sci. 2012;57:356–63. DOIPubMedGoogle Scholar
  26. Tomao  P, Ciceroni  L, D’Ovidio  MC, De Rosa  M, Vonesch  N, Iavicoli  S, et al. Prevalence and incidence of antibodies to Borrelia burgdorferi and to tick-borne encephalitis virus in agricultural and forestry workers from Tuscany, Italy. Eur J Clin Microbiol Infect Dis. 2005;24:457–63. DOIPubMedGoogle Scholar
  27. Jovanovic  D, Atanasievska  S, Protic-Djokic  V, Rakic  U, Lukac-Radoncic  E, Ristanovic  E. Seroprevalence of Borrelia burgdorferi in occupationally exposed persons in the Belgrade area, Serbia. Braz J Microbiol. 2015;46:807–14. DOIPubMedGoogle Scholar
  28. Kaya  AD, Parlak  AH, Ozturk  CE, Behcet  M. Seroprevalence of Borrelia burgdorferi infection among forestry workers and farmers in Duzce, north-western Turkey. New Microbiol. 2008;31:203–9.PubMedGoogle Scholar
  29. De Keukeleire  M, Robert  A, Luyasu  V, Kabamba  B, Vanwambeke  SO. Seroprevalence of Borrelia burgdorferi in Belgian forestry workers and associated risk factors. Parasit Vectors. 2018;11:277. DOIPubMedGoogle Scholar
  30. Podsiadły  E, Chmielewski  T, Karbowiak  G, Kędra  E, Tylewska-Wierzbanowska  S. The occurrence of spotted fever rickettsioses and other tick-borne infections in forest workers in Poland. Vector Borne Zoonotic Dis. 2011;11:985–9. DOIPubMedGoogle Scholar
  31. Wilhelmsson  P, Fryland  L, Lindblom  P, Sjöwall  J, Ahlm  C, Berglund  J, et al. A prospective study on the incidence of Borrelia burgdorferi sensu lato infection after a tick bite in Sweden and on the Åland Islands, Finland (2008-2009). Ticks Tick Borne Dis. 2016;7:71–9. DOIPubMedGoogle Scholar
  32. Liu  HB, Wei  R, Ni  XB, Zheng  YC, Huo  QB, Jiang  BG, et al. The prevalence and clinical characteristics of tick-borne diseases at One Sentinel Hospital in Northeastern China. Parasitology. 2019;146:161–7. DOIPubMedGoogle Scholar
  33. Steere  AC, Sikand  VK, Meurice  F, Parenti  DL, Fikrig  E, Schoen  RT, et al.; Lyme Disease Vaccine Study Group. Vaccination against Lyme disease with recombinant Borrelia burgdorferi outer-surface lipoprotein A with adjuvant. N Engl J Med. 1998;339:209–15. DOIPubMedGoogle Scholar

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