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Volume 28, Number 5—May 2022
Dispatch

Pathogens that Cause Illness Clinically Indistinguishable from Lassa Fever, Nigeria, 2018

Jonathan W. Ashcroft1, Adebola OlayinkaComments to Author , Nnaemeka Ndodo, Kuiama Lewandowski, Martin D. Curran, Chioma Dan Nwafor, Kingsley Madubuike, Helen Bagnall, Abdulmajid S. Musa, Adama Ahmad, Afolabi Akinpelu, Adesola Adeleye, Chukwuji Martin, Adejoke Akano, Michael Onoja, Akanimo Iniobong, Winifred Ukponu, Chinedu Arinze, Else Ilori, Nwando Mba, Benedict Gannon, Anthony Ahumibe, and Chikwe Ihekweazu
Author affiliations: Public Health England, London, UK (J.W. Ashcroft, H. Bagnall, B. Gannon); London School of Hygiene and Tropical Medicine, London (J.W. Ashcroft, H. Bagnall, B. Gannon); Nigeria Centre for Disease Control, Abuja, Nigeria (A. Olayinka, N. Ndodo, C. Dan Nwafor, K. Madubuike, A.S. Musa, A. Ahmad, A. Akinpelu, A. Adeleye, C. Martin, A. Akano, M. Onoja, A. Iniobong, W. Ukponu, C. Arinze, E. Ilori, N. Mba, A. Ahumibe, C. Ihekweazu); Public Health England, Porton Down, UK (K. Lewandowski); Clinical Microbiology and Public Health Laboratory, Public Health England, Cambridge, UK (M.D. Curran)

Main Article

Table 2

Array and MinION sequencing results for a subset of samples from patients who met the case definition for Lassa fever that were positive for bacteria, Nigeria, 2018*

Sample TAC hits Seq hit 1 (no. mapped reads) Seq hit 2 (no. mapped reads) Seq hit 3 (no. mapped reads) Seq hit 4 (no. mapped reads) Seq hit 5 (no. mapped reads)
307 Klebsiella pneumoniae Salmonella_hilA (108) Salmonella_ttr (55) Enterobacter (55) Enterobacter cloacae (55) Enterobacter (56)
165 Pan-Borrelia Spirochetes (27) None None None None
349 Escherichia coli generic E. coli (58) None None None None
344 Streptococcus Mec_A (591) Staphylococcus (657) Pseudomonas aeruginosa (3) Streptococcus. pyogenes (591) Streptococcus (591)
279 Streptococcus Streptococcus (8,837) None None None None

*Only samples with hits are shown. Seq hits at the genus level (number of reads). MinION described in references 5,6. TAC, TaqMan Array Cards (Applied Biosystems, https://www.thermofisher.com). Seq hit, sequencing hit.

Main Article

References
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  8. Nigeria Centre for Disease Control. An update of yellow fever outbreak in Nigeria [cited 2021 May 1]. https://ncdc.gov.ng/diseases/sitreps/?cat=10&name=An%20update%20of%20Yellow%20Fever%20outbreak%20in%20Nigeria

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1Current affiliation: Army, Defence Science & Technology, Ministry of Defence, London, UK.

Page created: February 25, 2022
Page updated: April 19, 2022
Page reviewed: April 19, 2022
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