Volume 30, Number 10—October 2024
Research
Economic Analysis of National Program for Hepatitis C Elimination, Israel, 20231
Table 2
Cost estimation per a resolved HCV case in an economic analysis of a national program for hepatitis C elimination, Israel, 2023*
Category |
HCV antibody tested |
Pending testing |
Program total cost |
|||||
No. patients |
Cost per patient |
Total cost |
No. patients |
Cost per patient |
Total cost |
|||
Initial serology | 555,083 | 23.5 | 13,044,451 | 308,826 | 23.5 | 7,257,411 | 20,301,862 | |
PCR for positive serology |
24,361 |
435.5 |
10,609,216 |
13,588† |
435.5 |
5,917,724 |
16,526,939 |
|
Treatment | 260,869,000‡ | |||||||
Posttreatment PCR for SVR | 13,379 | 435.5 | 5,826,555 | 8,697§ | 435.5 | 3,787,544 | 9,614,099 | |
No. SVR patients |
12,911 |
NA |
NA |
8,392¶ |
NA |
21,303 |
||
Total program cost |
307,311,900 |
|||||||
Cost per resolved HCV case | 14,426 ($3,606)# |
*A total of 863,909 persons were evaluated via serologic testing for HCV antibodies. Costs are in Israeli new shekel, except where indicated. HCV, hepatitis C virus; NA, not applicable; SVR, sustained viral response. †Given 4.4% positivity for HCV serology tested. ‡Overall treatment cost at Health Basket. §Given 64% positivity for HCV PCR testing. ¶Given 96.5% HCV resolution. #Conversion to US dollars based on 2012 data from ExchangeRates.org (https://www.exchangerates.org). Data should be inflation adjusted for accumulated inflation during 1999–2021.
1Preliminary results from this study were presented at the Israel National Institute for Health Policy Research conference; May 31, 2023; Tel Aviv, Israel.