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Volume 30, Number 10—October 2024
Dispatch

Mpox Epidemiology and Vaccine Effectiveness, England, 2023

Hannah CharlesComments to Author , Katie Thorley, Charlie Turner, Kirsty F. Bennet, Nick Andrews, Marta Bertran, Sema Mandal, Gayatri Amirthalingam, Mary E. Ramsay, Hamish Mohammed, and Katy Sinka
Author affiliation: UK Health Security Agency, London, UK

Main Article

Table 3

Vaccination status of mpox case-patients used to estimate vaccine effectiveness of various doses of Modified Vaccinia Ankara–Bavarian Nordic vaccine by using the screening method, England, 2023*

Doses Cases in 2023 Corrected cases† PCV, %
PPV, % PPV, sensitivity, %‡ VE, % (95% CI) VE sensitivity, % (95% CI)‡
0 54 65.4 52 16 30
1 20 24.2 19 38 32 84 (74–91) 65 (42–79)
2 30 36.4 29 45 38 80 (69–83) 56 (31–72)
Unknown 22
1 or 2 50 60.6 48 84 70 82 (74–88) 60 (41–73)
Total 126 126

*PCV, percentage of case-patients with the given number of doses; PPV, percentage of the population with the given number of doses obtained by matching each case to the population uptake 14 d before onset and averaging this across cases; VE, vaccine effectiveness. †22 case-patients with unknown vaccination status distributed among 0, 1, and 2 doses. ‡Based on the higher estimated denominator for gay, bisexual, men who have sex with men (107,088).

Main Article

Page created: August 27, 2024
Page updated: September 23, 2024
Page reviewed: September 23, 2024
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