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Volume 30, Number 11—November 2024
Research

Quantitative SARS-CoV-2 Spike Receptor-Binding Domain and Neutralizing Antibody Titers in Previously Infected Persons, United States, January 2021–February 2022

Anna BratcherComments to Author , Szu-Yu Kao, Kelly Chun, Christos J. Petropoulos, Adi V. Gundlapalli, Jefferson Jones1, and Kristie E.N. Clarke1
Author affiliation: Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia, USA (A. Bratcher); Alan Shawn Feinstein College of Education, University of Rhode Island, Kingston, Rhode Island, USA (S.-Y. Kao); Labcorp Esoterix, Calabasas, California, USA (K. Chun); Labcorp-Monogram Biosciences, South San Francisco, California, USA (C.J. Petropoulos); Centers for Disease Control and Prevention, Atlanta (A.V. Gundlapalli, J. Jones, K.E.N. Clarke)

Main Article

Figure 2

Pearson correlations in study of quantitative SARS-CoV-2 spike RBD and neutralizing antibody titers in previously infected persons, United States, January 2021–February 2022. A) Samples from children; B) samples from adults. Correlations are between the log10-transformed binding (anti-RBD IgG) and neutralizing antibody titers (NT50) for 744 specimens with available results in the Nationwide Commercial Laboratory Seroprevalence Survey database. Neutralizing antibody titers are against the ancestral spike protein. BAU, binding antibody units; NT50, 50% neutralization titer; RBD, receptor-binding domain.

Figure 2. Pearson correlations in study of quantitative SARS-CoV-2 spike RBD and neutralizing antibody titers in previously infected persons, United States, January 2021–February 2022. A) Samples from children; B) samples from adults. Correlations are between the log10-transformed binding (anti-RBD IgG) and neutralizing antibody titers (NT50) for 744 specimens with available results in the Nationwide Commercial Laboratory Seroprevalence Survey database. Neutralizing antibody titers are against the ancestral spike protein. BAU, binding antibody units; NT50, 50% neutralization titer; RBD, receptor-binding domain.

Main Article

1These co-senior authors contributed equally to this article.

Page created: September 30, 2024
Page updated: October 22, 2024
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