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Volume 30, Number 11—November 2024
Dispatch

Fatal Oropouche Virus Infections in Nonendemic Region, Brazil, 2024

Antonio Carlos Bandeira, Felicidade Mota Pereira, Arabela Leal, Sara P.O. Santos, Ana Claudia Barbosa, Marcia Sao Pedro Leal Souza, Daniele Ribeiro de Souza, Natalia Guimaraes, Vagner Fonseca, Marta Giovanetti, Luiz Carlos Junior Alcantara, André Alvarez A. Lessa, Ramon Costa Saavedra, Luiz Marcelo R. Tomé, Felipe Campos M. Iani, Rivia Mary Barros, Sandra Maria O. Purificação, Jaciara Prado de Jesus, Ricardo Rosário Fonseca, and Marcio Luis Valença AraújoComments to Author 
Author affiliations: Laboratório Central de Saúde Pública da Bahia, Salvador, Brazil (A.C. Bandeira, F. Mota Pereira, A. Leal, S.P.O. Santos); Diretoria de Vigilância Epidemiológica do Estado da Bahia, Salvador (A.C. Barbosa, M.S.P.L. Souza, D.R. de Souza, A.A.A. Lessa, R.C. Saavedra, S.M. de Oliveira da Purificação, J.P. de Jesus, M.L.V. Araújo); Fundação Ezequiel Dias, Belo Horizonte, Brazil (N. Guimaraes, F.C.M. Iani); University of the State of Bahia, Salvador (V. Fonseca); Universita Campus Bio-Medico di Roma, Rome, Italy (M. Giovanetti); Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil (M. Giovanetti); Instituto Rene Rachou, Fundação Oswaldo Cruz, Minas Gerais, Brazil (L.C.J. Alcantara, L.M.R. Tomé); Superintendência de Vigilância em Saúde, Salvador (R.M. Barros); Santa Casa de Misericórdia de Valença Hospital, Valença, Brazil (R.R. Fonseca); Instituto Federal de Educação, Salvador (M.L.V. Araújo)

Main Article

Table 3

Molecular biology and serologic test results in 2 cases of fatal Oropouche virus infection in nonendemic region, Brazil, 2024*

Laboratory test
 Patient 1
 Patient 2
qRT-PCR
Dengue virus Undetectable Undetectable
Chikungunya virus Undetectable Undetectable
Zika virus Undetectable Undetectable
Mayaro virus Undetectable Undetectable
Oropouche virus, Ct value Detectable, 16 Detectable, 8
qPCR
Leptospira Not done Undetectable
Neisseria meningitidis Undetectable Undetectable
Streptococcus pneumoniae Undetectable Undetectable
Hemophilus influenzae Undetectable Undetectable
Serology
Dengue virus IgM Nonreactive Nonreactive
Leptospira IgM Nonreactive Nonreactive
Chikungunya virus IgM Nonreactive Nonreactive
Hepatitis C virus IgG, IgM Not done Nonreactive
Hepatitis B virus IgG, IgM Not done Nonreactive
Hepatitis A virus IgG, IgM Not done Nonreactive

*Performed in serum samples, except for Leptospira qPCR, which was performed on whole blood. Patient 1 samples collected 4 days after symptom onset; patient 2 samples collected 5 days after symptom onset. Ct, cycle threshold; qPCR, quantitative PCR; qRT-PCR, quantitative reverse transcription PCR.

Main Article

Page created: September 10, 2024
Page updated: October 22, 2024
Page reviewed: October 22, 2024
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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