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Volume 31, Number 2—February 2025
Research

Epidemiologic and Genomic Surveillance of Vibrio cholerae and Effectiveness of Single-Dose Oral Cholera Vaccine, Democratic Republic of the Congo

Christine Marie George1Comments to Author , Alves Namunesha1, Kelly Endres, Willy Felicien, Presence Sanvura, Jean-Claude Bisimwa, Jamie Perin, Justin Bengehya, Ghislain Maheshe, Cirhuza Cikomola, Lucien Bisimwa, Alain Mwishingo, David A. Sack, and Daryl Domman
Author affiliation: Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA (C.M. George, K. Endres, J. Perin, D.A. Sack); Université Catholique de Bukavu, Bukavu, Democratic Republic of the Congo (A. Namunesha, W. Felicien, P. Sanvura, J.-C. Bisimwa, G. Maheshe, C. Cikomola, L. Bisimwa, A. Mwishingo); Ministère de la Santé, Bukavu (J. Bengehya); University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA (D. Domman)

Main Article

Figure 4

Phylogenetic analysis of Vibrio cholerae strains in study of V. cholerae transmission and effectiveness of single-dose oral cholera vaccine, DRC. Maximum-likelihood phylogenetic trees were prepared to compare V. cholerae seventh pandemic El Tor (7PET) isolates. A) Globally representative phylogeny of 1,428 7PET strains; 5 representative isolates from this study (red) were placed within the larger context of those 7PET strains. Tree was rooted on the A6 strain. Branch colors indicate geographic origin of the strain. B) Phylogeny of the T10/AFR10 lineage of V. cholerae. Colors indicate different V. cholerae lineages. Representative isolates from this study (n = 46; red) were placed within the context of 221 T10/AFR10 lineage strains. Tree was rooted on the reference strain N16961. Scale bars indicate nucleotide substitutions per site. DRC, Democratic Republic of the Congo.

Figure 4. Phylogenetic analysis of Vibrio cholerae strains in study of V. cholerae transmission and effectiveness of single-dose oral cholera vaccine, DRC. Maximum-likelihood phylogenetic trees were prepared to compare V. cholerae seventh pandemic El Tor (7PET) isolates. A) Globally representative phylogeny of 1,428 7PET strains; 5 representative isolates from this study (red) were placed within the larger context of those 7PET strains. Tree was rooted on the A6 strain. Branch colors indicate geographic origin of the strain. B) Phylogeny of the T10/AFR10 lineage of V. cholerae. Colors indicate different V. cholerae lineages. Representative isolates from this study (n = 46; red) were placed within the context of 221 T10/AFR10 lineage strains. Tree was rooted on the reference strain N16961. Scale bars indicate nucleotide substitutions per site. DRC, Democratic Republic of the Congo.

Main Article

1These first authors contributed equally to this article.

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