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Volume 31, Number 4—April 2025
Research Letter

Coxiella burnetii Infections Identified by Molecular Methods, United States, 2006–2023

Caroline K. Maki, Thao T. Truong, Johanna S. Salzer, Nicolette Bestul, Brad T. Cookson, Gilbert J. Kersh, Stephen J. Salipante, Joshua A. Lieberman1, and David W. McCormick1Comments to Author 
Author affiliation: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (C.K. Maki, J.S. Salzer, N. Bestul, G.J. Kersh, D.W. McCormick); Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee, USA (C.K. Maki); University of Washington, Seattle, Washington, USA (T.T. Truong, B.T. Cookson, S.J. Salipante, J.A. Lieberman)

Main Article

Table 1

Characteristics of case-patients with invasive Coxiella burnetii infection identified by molecular methods, United States, 2006–2023*

Characteristic No. (%)
Sex
M 19 (56)
F 9 (27)
NA
 6 (18)
State of residence
California 9 (27)
Washington 7 (21)
Ohio 6 (18)
Utah 4 (12)
Texas 2 (6)
Oregon 2 (6)
Montana 1 (3)
Virginia 1 (3)
Kentucky 1 (3)
Nevada
 1 (3)
Specimen type, n = 35†
Cardiac 30 (86)
Aortic‡ 18 (78)
Mitral 5 (22)
Pulmonary 1 (50)
Tricuspid 1 (50)
Heart NOS§
 5 (17)
Not cardiac 5 (14)
Synovial fluid 1 (2)
Knee joint 1 (2)
Chest cyst fluid 1 (2)
Psoas abscess 1 (2)
Retrocaval abscess 1 (2)

*Median age of patients at sample collection was 62.5 years; age range 23–79 years. NA, not available; NOS, not otherwise specified. †One patient had 2 positive specimens (tricuspid and mitral valve). ‡Six aortic specimens were prosthetic valves. §Two heart NOS specimens were prosthetic valves.

Main Article

1These senior authors contributed equally to this article.

Page created: February 28, 2025
Page updated: March 12, 2025
Page reviewed: March 12, 2025
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