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Volume 31, Number 4—April 2025
Research

Oz Virus Infection in 6 Animal Species, Including Macaques, Bears, and Companion Animals, Japan

Aya Matsuu1, Kango Tatemoto, Keita Ishijima, Ayano Nishino, Yusuke Inoue, Eunsil Park, Hiroo Tamatani, Junji Seto, Hideo Higashi, Yuichi Fukui, Takashi Noma, Kandai Doi, Rumiko Nakashita, Haruhiko Isawa, Shinji Kasai, and Ken MaedaComments to Author 
Author affiliation: National Institute of Infectious Diseases, Tokyo, Japan (A. Matsuu, K. Tatemoto, K. Ishijima, A. Nishino, Y. Inoue, E. Park, H. Isawa, S. Kasai, K. Maeda); Picchio Wildlife Research Center, Karuizawa, Japan (H. Tamatani); Yamagata Prefectural Institute of Public Health, Yamagata, Japan (J. Seto); Wildlife Workshop, Yamagata (H. Higashi); Komachi Animal Hospital, Tsukuba, Japan (Y. Fukui); Kubota Animal Clinic, Ozu, Japan (T. Noma); Forestry and Forest Products Research Institute, Tsukuba (K. Doi, R. Nakashita)

Main Article

Figure 3

Comparison of the results of virus-neutralization tests (positive vs. negative) and ELISAs against Oz virus in serum samples from 6 tested animal species, Japan, 2007–2023. A) Wild boar (Sus scrofa leucomystax). B) Sika deer (Cervus nippon). C) Japanese macaques (Macaca fuscata). D) Asian black bear (Ursus thibetanus). E) Dog (Canis lupus familiaris). F) Cat (Felis silvestris catus). Red dashed line indicates optimal cutoff value of ELISA, which was determined by a 2-graph receiver-operating characteristic curve. The ELISA cutoff value was not determined in dogs and cats because of the low numbers of seropositive companion animals. Horizontal lines indicate means and error bars SDs. OD, optical density.

Figure 3. Comparison of the results of virus-neutralization tests (positive vs. negative) and ELISAs against Oz virus in serum samples from 6 tested animal species, Japan, 2007–2023. A) Wild boar (Sus scrofa leucomystax). B) Sika deer (Cervus nippon). C) Japanese macaques (Macaca fuscata). D) Asian black bear (Ursus thibetanus). E) Dog (Canis lupus familiaris). F) Cat (Felis silvestris catus). Red dashed line indicates optimal cutoff value of ELISA, which was determined by a 2-graph receiver-operating characteristic curve. The ELISA cutoff value was not determined in dogs and cats because of the low numbers of seropositive companion animals. Horizontal lines indicate means and error bars SDs. OD, optical density.

Main Article

1Current affiliation: Nihon University, Tokyo, Japan.

Page created: February 12, 2025
Page updated: March 07, 2025
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