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Volume 9, Number 12—December 2003
Research

Mycobacterium abscessus and Children with Cystic Fibrosis

Isabelle Sermet-Gaudelus*, Muriel Le Bourgeois*, Catherine Pierre-Audigier*, Catherine Offredo*, Didier Guillemot†, Sophie Halley*, Chantal Akoua-Koffi*, Véronique Vincent†, Valérie Sivadon-Tardy‡, Agnès Ferroni*, Patrick Berche*, Pierre Scheinmann*, Gérard Lenoir*, and Jean-Louis Gaillard‡Comments to Author 
Author affiliations: *Hôpital Necker-Enfants Malades, Assistance Publique–Hôpitaux de Paris, Paris, France; †Institut Pasteur, Paris, France; ‡Hôpital Raymond Poincaré, Assistance Publique–Hôpitaux de Paris, Garches, France

Main Article

Table

Chronology of case-patients with Mycobacterium abcessus isolationa

Case no. Age (y)/sex Date of first isolation No. of pos. cultures/total AFB culturesb No. of pos. AFB smears/total AFB smearsb,c hsp65 genomovard Sputum
microbiologic resultse
1
 2.5 / M
 Jan 1996
 37/48
 19/31
 (+++)
 -6
 Negative
2
 13 / F
 Feb 1996
 2/14
 0/9
T
 Pseudomonas aeruginosa
3
 15 / F
 Apr 1996
 3/41
 0/21
-5a
 P. aeruginosa
4
 16 / M
 Apr 1996
 5/8
 1/6
 (+)
 T
 P. aeruginosa, Staphylococcus aureus, Aspergillus fumigatus
5
 14 / F
 May 1996
 8/11
 4/8
 (++)
 T
 P. aeruginosa, S. aureus, A. fumigatus
6
 10 / M
 May 1996
 4/25
 0/12
T
 P. aeruginosa, Alcaligenes xylosoxidans
7
 9 / F
 May 1996
 8/8
 4/7
 (+++)
 T
 P. aeruginosa, Aspergillus fumigatus
8
 2.5 / F
 Nov 1997
 4/6
 2/5
 (++)
 -5a
 Negative
9
 7 / F
 July 1998
 2/24
 0/7
-5a
 S. aureus
10
 17 / M
 Sept 1998
 3/9
 0/6
T
 S. aureus, Haemophilus influenzae, Stenotrophomonas maltophilia, A. fumigatus
11
 8 / F
 Sept 1998
 3/12
 0/4
T
 P. aeruginosa, Staphylococcus aureus
12
 18/F
 July 1999
 1/5
 0/3
T
 P. aeruginosa, A. fumigatus
13
 9/M
 Sept 1999
 1/6
 0/3
-6
 S. aureus
14
 16/M
 Oct 1999
 5/13
 4/6
 (+)
 -5a
 S. aureus, A. fumigatus
15 22/F Nov 1999 1/6 0/3 -6 P. aeruginosa, S. aureus

aAFB, acid-fast bacilli.
bSamples obtained from patients from January 1996 to December 2000; only samples obtained before the administration of antimycobacterial drugs are considered in treated patients.
cSymbols in parentheses: AFB density.
dSee Methods.
eOrganisms recovered from at least three sputum samples within the 12 months before the first isolation of M. abscessus.

Main Article

Page created: February 07, 2011
Page updated: February 07, 2011
Page reviewed: February 07, 2011
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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