Volume 9, Number 6—June 2003
Research
Serogroup W-135 Meningococcal Disease during the Hajj, 2000
Jairam R. Lingappa*
, Abdullah M. Al-Rabeah†, Rana Hajjeh*, Tajammal Mustafa†, Adel Fatani†, Tami Al-Bassam†, Amira Badukhan†, Abdulhafiz Turkistani†, Nassen Al-Hamdan†, Mohamed Al-Jeffri†, Yaqoub Al Mazrou†, Bradley A. Perkins*, Tanja Popovic*, Leonard W. Mayer*, and Nancy E. Rosenstein*
, Abdullah M. Al-Rabeah†, Rana Hajjeh*, Tajammal Mustafa†, Adel Fatani†, Tami Al-Bassam†, Amira Badukhan†, Abdulhafiz Turkistani†, Nassen Al-Hamdan†, Mohamed Al-Jeffri†, Yaqoub Al Mazrou†, Bradley A. Perkins*, Tanja Popovic*, Leonard W. Mayer*, and Nancy E. Rosenstein*
Table 2
Clinical characteristics of patients with confirmed meningococcal disease, Saudi Arabiaa
| Feature | All cases, n=253 (%) | Serogroup-specific cases, n (%) |
|
|---|---|---|---|
| W-135, n=93 | A, n=60 | ||
| Seen by clinician <1 day after symptom onset |
125 (49) |
45 (48) |
31 (52) |
| Semiconscious, comatose, or deadb |
146 (62) |
57 (63) |
33 (58) |
| Positive blood cultureb |
72/140 |
55 (79) |
15 (29) |
| Sepsis without meningitis |
23 (9) |
19 (20) |
4 (7) |
| Admitted to intensive careb |
51/212 (24) |
27 (35) |
7 (14) |
| >1-day intensive care requiredb |
33/202 (16) |
19 (26) |
3 (6) |
| Death (case-fatality rate) | 70 (28) | 27 (29) | 16 (27) |
aIdentified by retrospective surveillance (January 24–June 5, 2000, in Jeddah, Mecca, Medina, Saudi Arabia. Cases of serogroup B and C disease (four cases each) as well as cases of unknown serogroup are not shown. Denominator for all confirmed cases is 253 unless stated otherwise (changes in denominators are due to missing values); denominator for serogroup-specific percentages is the total serogroup-specific disease.
bComparison of characteristics for serogroup W-135 versus serogroup A with Fisher exact p value <0.05.
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