Dengue Virus Serotype 3 Origins and Genetic Dynamics, Jamaica
Shanice A. Redman
1, Lester J. Perez
1, Kenn Forberg, Keisha Francis, Jerome P. Walker, Tamara K. Thompson, Heather Phillips, Gavin A. Cloherty, Michael G. Berg, and Joshua J. Anzinger
Author affiliations: Abbott Pandemic Defense Coalition, Kingston, Jamaica (S.A. Redman, K. Francis, J.P. Walker, T.K. Thompson, H. Phillips, J.J. Anzinger); The University of the West Indies, Kingston (S.A. Redman, K. Francis, J.P. Walker, T.K. Thompson, H. Phillips, J.J. Anzinger); Abbott Laboratories, Abbott Park, Illinois, USA (L.J. Perez, K. Forberg, G.A. Cloherty, M.G. Berg); Abbott Pandemic Defense Coalition, Abbott Park (L.J. Perez, K. Forberg, G.A. Cloherty, M.G. Berg); Global Virus Network, Baltimore, Maryland, USA (J.J. Anzinger)
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Figure 4
Figure 4. Envelope glycoprotein 3-dimensional structures (structure 7a3s; RCSB Protein Data Bank, https://www.rcsb.org) from dengue virus serotype 3 strains in Jamaica. Red indicates protein domain I, yellow indicates domain II, and blue indicates domain III. Gray spheres indicate mutations identified across various TGs. Arrows indicate mutations detected by site models. E621Q (faded text) is in the loop region not visible in the crystal structure. TG, temporal group.
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