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Volume 30, Number 10—October 2024
Dispatch

Autochthonous Human Babesia divergens Infection, England

Guillermo A. Zabala, Robert Lever, Xin Hui Chan, Henrietta Bristowe, Emer Kilbride, David Richards, Mark Daly, Michael Brown, Nick Johnson, Laura Eve Nabarro, Hanif Esmail, Gauri Godbole, and Peter L. ChiodiniComments to Author 
Author affiliations: Infectious Diseases Data Observatory, Oxford, UK (G.A. Zambala); Hospital for Tropical Diseases, University College Hospital, London, UK (G.A. Zabala, R. Lever, X.H. Chan, H. Bristowe, E. Kilbride, M. Brown, L.E. Nabarro, H. Esmail, G. Godbole, P.L. Chiodini); London School of Hygiene and Tropical Medicine, London (R. Lever, M. Brown, G. Godbole, P.L. Chodini); Centre for Tropical Medicine and Global Health, University of Oxford, Oxford (X.H Chan); North Devon District Hospital, Barnstaple, UK (D. Richards, M. Daly); Animal and Plant Health Agency, Surrey, UK (N. Johnson); Institute for Global Health and Medical Research Council Clinical Trials Unit, University College London, London (H. Esmail)

Main Article

Table

Course of parasitemia during admission and interventions used in a case of autochthonous human Babesia divergens infection, England*

Days after admission % Parasitemia† Intervention
0 18 IV quinine, 10 mg/kg every 8 h; IV clindamycin, 600 mg every 6 h
1
9
2
2.4
IV quinine, 10 mg/kg every 8 h; IV clindamycin, 600 mg every 6 h; nasogastric atovaquone, 750 mg every 12 h
3 1.3 4 units red blood cells via manual exchange transfusion
4
0.9
5 0.07 IV azithromycin, 250 mg every 24 h; IV clindamycin, 600 mg every 6 h; nasogastric atovaquone 750 mg every 12 h
6 0.1
7
0.08
8 0.05 IV doxycycline, 200 mg every 24 h
9 0.03
10
0.03
11 0.02 2 units of M- and S-antigen–negative red blood cells
12 0.01
13 0.01
14
0
15 0 Antiparasitic agents discontinued

*IV, intravenous. †Percentage of parasitized erythrocytes detected by light microscopy of thin blood films.

Main Article

Page created: August 28, 2024
Page updated: September 23, 2024
Page reviewed: September 23, 2024
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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