Volume 30, Number 9—September 2024
Research
Effects of Rotavirus Vaccination Coverage among Infants on Hospital Admission for Gastroenteritis across All Age Groups, Japan, 2011–2019
Kenji Kishimoto, Susumu Kunisawa, Kiyohide Fushimi, and Yuichi Imanaka
Table 3
Generalized estimating equations analyses, restricted to data from rotavirus epidemic seasons (February–April), to estimate the impact of rotavirus vaccination coverage on the monthly number of gastroenteritis hospitalizations across all age groups, Japan, 2011–2019*
| Vaccination coverage, % | IRR (95% CI) |
|||||||
|---|---|---|---|---|---|---|---|---|
| Overall, n = 69,025 |
Age-ineligible for vaccination, n = 56,605 |
Immunocompromised, n = 8,878 |
||||||
| Crude | Adjusted† | Crude | Adjusted† | Crude | Adjusted† | |||
| <40 |
Referent |
Referent |
Referent |
|||||
| 40–49 |
0.93 (0.91–0.95) |
0.93 (0.90–0.95) |
0.96 (0.93–0.98) |
0.97 (0.94–1.00) |
1.03 (0.95–1.11) |
1.01 (0.94–1.10) |
||
| 50–59 |
0.92 (0.90–0.94) |
0.91 (0.88–0.95) |
0.98 (0.95–1.00) |
1.00 (0.96–1.04) |
1.05 (0.98–1.12) |
1.03 (0.94–1.12) |
||
| 60–69 |
0.91 (0.89–0.93) |
0.90 (0.86–0.94) |
0.96 (0.93–0.98) |
1.00 (0.95–1.05) |
1.01 (0.95–1.07) |
0.98 (0.88–1.09) |
||
| 70–79 |
0.90 (0.88–0.92) |
0.89 (0.84–0.94) |
0.94 (0.92–0.97) |
1.00 (0.94–1.07) |
1.03 (0.97–1.10) |
0.99 (0.87–1.13) |
||
| ≥80 | 0.89 (0.86–0.92) | 0.87 (0.81–0.94) | 0.90 (0.86–0.93) | 0.97 (0.90–1.05) | 1.04 (0.95–1.14) | 1.00 (0.85–1.17) | ||
*IRR, incidence rate ratio. †Adjusted for age group, year, and month.
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