Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 26, Number 2—February 2020
Research

Interspecies Transmission of Reassortant Swine Influenza A Virus Containing Genes from Swine Influenza A(H1N1)pdm09 and A(H1N2) Viruses

Helen E. EverettComments to Author , Bethany Nash, Brandon Z. Londt1, Michael D. Kelly, Vivien Coward, Alejandro Nunez, Pauline M. van Diemen, Ian H. Brown, and Sharon M. Brookes
Author affiliations: Animal and Plant Health Agency, Weybridge, UK

Main Article

Figure 2

Histopathologic and immunohistochemical analyses of tissues from pigs or ferrets directly infected with swine influenza A(H1N2) reassortant virus showing mild disease. A, B) Histopathologic scores for pigs (A) or ferrets (B) are calculated as mean for 4 animals at 3 dpi and 5 dpi or 2 animals at 7 dpi. Error bars indicate SEM. Tissues are indicated in anatomic order from the upper to lower respiratory tract. C–G) Immunohistochemical labeling for influenza A virus nucleoprotein (brown) is shown

Figure 2. Histopathologic and immunohistochemical analyses of tissues from pigs or ferrets directly infected with swine influenza A(H1N2) reassortant virus showing mild disease. A, B) Histopathologic scores for pigs (A) or ferrets (B) are calculated as mean for 4 animals at 3 dpi and 5 dpi or 2 animals at 7 dpi. Error bars indicate SEM. Tissues are indicated in anatomic order from the upper to lower respiratory tract. C–G) Immunohistochemical labeling for influenza A virus nucleoprotein (brown) is shown for tissue sections from pig respiratory turbinates at 5 dpi (C), ferret respiratory turbinates at 7 dpi (D), pig lung at 5 dpi (E), and ferret lung at 7 dpi (F) (original magnification ×20 for C, D, E, and F). Ferret salivary gland tissue at 76 dpi (G) shows intense labeling (original magnification ×10). dpi, days postinoculation; L, left; LL, lung lobe; LN, lymph node; mid, middle; R, right.

Main Article

1Current affiliation: hVIVO Services Limited, London, UK.

Page created: January 17, 2020
Page updated: January 17, 2020
Page reviewed: January 17, 2020
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external