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Volume 30, Number 10—October 2024
Research

Pathogenicity of Highly Pathogenic Avian Influenza A(H5N1) Viruses Isolated from Cats in Mice and Ferrets, South Korea, 2023

Il-Hwan Kim1, Jeong-Hyun Nam1, Chi-Kyeong Kim, Yong Jun Choi, Hyeokjin Lee, Bo Min An, Nam-Joo Lee, Hyoseon Jeong, Su-Yeon Lee, Sang-Gu Yeo, Eun-Kyoung Lee, Youn-Jeong Lee, Jee Eun Rhee, Sang Won Lee, Youngmee Jee, and Eun-Jin KimComments to Author 
Author affiliations: Korea Disease Control and Prevention Agency, Cheongju, South Korea (I.-H. Kim, J.-H. Nam, C.-K. Kim, Y.J. Choi, H. Lee, B.M. An, N.-J. Lee, H. Jeong, S.-Y. Lee, S.-G. Yeo, J.E. Rhee, S.W. Lee, Y. Jee, E.-J. Kim); Animal and Plant Quarantine Agency, Gimcheon, South Korea (E.-K. Lee, Y.-J. Lee)

Main Article

Figure 5

Survival rates after ferret-to-ferret contact transmission in study of pathogenicity of highly pathogenic avian influenza A(H5N1) viruses isolated from cats, South Korea, 2023. Viruses were isolated from 2 cats and 1 duck. A) A/feline/Korea/M302-6/2023; B) A/feline/Korea/M305-7/2023; C) A/duck/Korea/H493/2022. We intranasally inoculated 1 ferret with 1 mL of 103 50% median lethal dose of each virus (1 ferret/virus) and then housed serologically naive ferrets (n = 2) in the same cage the next day (1 cage/virus). Survival rates for the inoculated and naive ferrets were measured.

Figure 5. Survival rates after ferret-to-ferret contact transmission in study of pathogenicity of highly pathogenic avian influenza A(H5N1) viruses isolated from cats, South Korea, 2023. Viruses were isolated from 2 cats and 1 duck. A) A/feline/Korea/M302-6/2023; B) A/feline/Korea/M305-7/2023; C) A/duck/Korea/H493/2022. We intranasally inoculated 1 ferret with 1 mL of 103 50% median lethal dose of each virus (1 ferret/virus) and then housed serologically naive ferrets (n = 2) in the same cage the next day (1 cage/virus). Survival rates for the inoculated and naive ferrets were measured.

Main Article

1These authors contributed equally to this article.

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