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Volume 26, Number 11—November 2020
Research

Modeling Treatment Strategies to Inform Yaws Eradication

Alex HolmesComments to Author , Michael J. Tildesley, Anthony W. Solomon, David C.W. Mabey, Oliver Sokana, Michael Marks, and Louise Dyson
Author affiliations: Mathematics Institute, University of Warwick, Coventry, UK (A. Holmes, M.J. Tildesley, L. Dyson); University of Warwick School of Life Sciences, Coventry (M.J. Tildesley, L. Dyson); Hospital for Tropical Diseases, London, UK (A.W. Solomon, D.C.W. Mabey, M. Marks); London School of Hygiene and Tropical Medicine, London (A.W. Solomon, D.C.W. Mabey, M. Marks); Ministry of Health and Medical Services, Honiara, Solomon Islands (O. Sokana)

Main Article

Figure 4

Probability of local elimination of transmission under different intervention strategies consisting of >2 rounds of TCT and >2 rounds of TTT, with varying numbers of additional rounds of TTT (blue) or TCT (green). Each twice-yearly round of TCT has 80% coverage, whereas TTT has 100% coverage and treatment is assumed to have 95% efficacy. All rounds of TCT are performed first before any rounds of TTT begin, which are then also performed twice yearly. Parameters are inferred from data collected from the Solomon Islands in 2013. TCT, total community treatment; TTT, total targeted treatment.

Figure 4. Probability of local elimination of transmission under different intervention strategies consisting of >2 rounds of TCT and >2 rounds of TTT, with varying numbers of additional rounds of TTT (blue) or TCT (green). Each twice-yearly round of TCT has 80% coverage, whereas TTT has 100% coverage and treatment is assumed to have 95% efficacy. All rounds of TCT are performed first before any rounds of TTT begin, which are then also performed twice yearly. Parameters are inferred from data collected from the Solomon Islands in 2013. TCT, total community treatment; TTT, total targeted treatment.

Main Article

Page created: August 18, 2020
Page updated: October 17, 2020
Page reviewed: October 17, 2020
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